Start Submission Become a Reviewer

Reading: Recommendations for the Use of Operational Electronic Health Record Data in Comparative Effe...

Download

A- A+
dyslexia friendly

Model / Framework

Recommendations for the Use of Operational Electronic Health Record Data in Comparative Effectiveness Research

Authors:

William Hersh ,

Oregon Health & Science University
X close

James Cimino,

National Institutes of Health Clinical Center
X close

Philip R.O. Payne,

The Ohio State University
X close

Peter Embi,

The Ohio State University
X close

Judith Logan,

Oregon Health & Science University
X close

Mark Weiner,

AstraZeneca
X close

Elmer V. Bernstam,

The University of Texas Health Science Center at Houston
X close

Harold Lehmann,

Johns Hopkins University
X close

George Hripcsak,

Columbia University
X close

Timothy Hartzog,

Medical University of South Carolina
X close

Joel Saltz

Emory University
X close

Abstract

There is an increasing amount of clinical data in operational electronic health record (EHR) systems. Such data provide substantial opportunities for their re-use for many purposes, including comparative effectiveness research (CER). In a previous paper, we identified a number of caveats related to the use of such data, noting that they may be inaccurate, incomplete, transformed in ways that undermine their meaning, unrecoverable for research, of unknown provenance, of insufficient granularity, or incompatible with research protocols. In this paper, we provide recommendations for overcoming these caveats with the goal of leveraging such data to benefit CER and other health care activities. These recommendations include adaptation of “best evidence” approaches to use of data; processes to evaluate availability, completeness, quality, and transformability of data; creation of tools to manage data and their attributes; determination of metrics for assessing whether data are “research grade”; development of methods for comparative validation of data; construction of a methodology database for methods involving use of clinical data; standardized reporting methods for data and their attributes; appropriate use of informatics expertise; and a research agenda to determine biases inherent in operational data and to assess informatics approaches to their improvement.
How to Cite: Hersh W, Cimino J, Payne PRO, Embi P, Logan J, Weiner M, et al.. Recommendations for the Use of Operational Electronic Health Record Data in Comparative Effectiveness Research. eGEMs (Generating Evidence & Methods to improve patient outcomes). 2013;1(1):14. DOI: http://doi.org/10.13063/2327-9214.1018
Published on 01 Oct 2013.
Peer Reviewed

Downloads

  • PDF (EN)